Alkylating agent

Introduction: Alkylating agent

Description of Alkylating agent

Alkylating agent: A drug that is used in the treatment of cancer. It interferes with the cell's DNA and inhibits cancer cell growth.
Source: National Institute of Health

Alkylating agent: Agents that add alkyl groups to nucleophilic moieties through covalent linkages and exhibit cytotoxic effects through the alkylation of DNA.
Source: Diseases Database

Alkylating agent: chemical agent that can add alkyl groups (for example, ethyl or methyl groups) to another molecule; many mutagens act through alkylation.
Source: CRISP

Alkylating agent: Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
Source: MeSH 2007

Alkylating agent: Related Topics

These medical condition or symptom topics may be relevant to medical information for Alkylating agent:

• Agent
• Drug
• Drug symptoms (36 causes)
• Chemical
• Formation
• Covalent
• Tissue
• Part
• Compound
• Carcinogenic

Terms associated with Alkylating agent:

More specific terms for Alkylating agent:

• Antineoplastic Agents, Alkylating

Source - MeSH 2007

• busulfan
• ifosfamide
• imidazole carboxamide
• nitrogen mustard
• nitrosourea

Source - CRISP

Broader terms for Alkylating agent

• Molecular Mechanisms of Action
• Noxae

Source - MeSH 2007

• reagent /indicator

Source - CRISP

Other terms that may be related to Alkylating agent:

• antineoplastic

Source: CRISP

Hierarchical classifications of Alkylating agent

The following list attempts to classify Alkylating agent into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Chemical Actions and Uses
  • Pharmacologic Actions
    • Molecular Mechanisms of Action
      • Alkylating Agents

MeSH 2007 Hierarchy

• Chemical Actions and Uses
  • Toxic Actions
    • Noxae
      • Alkylating Agents

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• Medical Acronymns/Abbreviations

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