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Aminoglutethimide

Introduction: Aminoglutethimide

Description of Aminoglutethimide

Aminoglutethimide: An anticancer drug that belongs to the family of drugs called nonsteroidal aromatase inhibitors. Aminoglutethimide is used to decrease the production of sex hormones (estrogen in women or testosterone in men) and suppress the growth of tumors that need sex hormones to grow.
Source: National Institute of Health

Aminoglutethimide: A synthetic derivative of the sedative and anticonvulsant glutethimide with anti-steroid properties. Originally used as an anticonvulsant, aminoglutethimide also blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of cholesterol to pregnenolone. In addition, this agent blocks the peripheral aromatization of androgenic precursors to estrogens. Aminoglutethimide does not suppress ovarian estrogen production. (NCI04)
Source: Diseases Database

Aminoglutethimide: USP lists as an antineoplastic and an "adrenocortical suppressant."
Source: CRISP

Aminoglutethimide: An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p454).
Source: MeSH 2007

Aminoglutethimide: Related Topics

These medical condition or symptom topics may be relevant to medical information for Aminoglutethimide:

Terms associated with Aminoglutethimide:

Broader terms for Aminoglutethimide

Source - MeSH 2007

Source - CRISP

Hierarchical classifications of Aminoglutethimide

The following list attempts to classify Aminoglutethimide into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

External links related to: Aminoglutethimide

Source: Diseases Database

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