Apolipoproteins E

Introduction: Apolipoproteins E

Description of Apolipoproteins E

Apolipoproteins E: A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.
Source: MeSH 2007

Terms associated with Apolipoproteins E:

Terms Similar to Apolipoproteins E:

• Apo-E

Source - MeSH 2007

More specific terms for Apolipoproteins E:

• Apolipoprotein E3
• Apolipoprotein E4
• Apolipoprotein E2

Source - MeSH 2007

Broader terms for Apolipoproteins E

• Apolipoproteins

Source - MeSH 2007

Hierarchical classifications of Apolipoproteins E

The following list attempts to classify Apolipoproteins E into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Lipids
  • Lipoproteins
    • Apolipoproteins
      • Apolipoproteins E

MeSH 2007 Hierarchy

• Amino Acids, Peptides, and Proteins
  • Proteins
    • Apoproteins
      • Apolipoproteins
        • Apolipoproteins E

MeSH 2007 Hierarchy

• Amino Acids, Peptides, and Proteins
  • Proteins
    • Lipoproteins
      • Apolipoproteins
        • Apolipoproteins E

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