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Dictionary » Augmerosen


Introduction: Augmerosen

Description of Augmerosen

Augmerosen: A phosphorothioate antisense oligonucleotide. Targeted to the initiation codon region of the bcl-2 mRNA, oblimersen inhibits bcl-2 mRNA translation, resulting in decreased expression of the bcl-2 protein, an apoptotic inhibitor expressed in some types of cancer and linked to tumor drug resistance. This agent may enhance the efficacy of standard cytotoxic chemotherapy. (NCI04)
Source: Diseases Database

Augmerosen: Related Topics

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Source: Diseases Database

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More Medical Dictionary Topics

  • Chromosome 15, trisomy mosaicism
  • Chromosome 15q deletion syndrome
  • Chromosome 15q duplication syndrome
  • Chromosome 15q monosomy
  • Chromosome 15q tetrasomy syndrome
  • Chromosome 15q triplication syndrome
  • Chromosome 15q, partial deletion
  • Chromosome 15q, tetrasomy
  • Chromosome 15q, trisomy
  • Chromosome 16, trisomy
  • Chromosome 16, trisomy 16p
  • Chromosome 16, trisomy 16q

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