Campath 1H

Introduction: Campath 1H

Description of Campath 1H

Campath 1H: A recombinant DNA-derived humanized monoclonal antibody directed against the cell surface glycoprotein, CD52. Alemtuzumab is an IgG1 kappa with human variable framework and constant regions, and complementarity-determining regions derived from a rat monoclonal antibody. This agent selectively binds to CD52, thereby triggering a host immune response that results in lysis of CD52 + cells. CD52 is a glycoprotein expressed on the surface of essentially all normal and malignant B and T cells, a majority of monocytes, macrophages and natural killer (NK) cells, a subpopulation of granulocytes, and tissues of the male reproductive system. (NCI04)
Source: Diseases Database

Campath 1H: Related Topics

These medical condition or symptom topics may be relevant to medical information for Campath 1H:

• Recombinant
• DNA
• Antibody
• Cell
• Surface
• Glycoprotein
• CD52
• Alemtuzumab
• Human
• Variable

Terms associated with Campath 1H:

Terms Similar to Campath 1H:

• Alemtuzumab

Source: Diseases Database

External links related to: Campath 1H

• CancerSourceMD.Com Drug Guide
• MabCampath 30mg/ml concentrate for solution for infusion , SPC from the eMC
• Campath Online, Description, Chemistry, Ingredients - Alemtuzumab - RxList Monographs

Source: Diseases Database

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