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Capecitabine

Introduction: Capecitabine

Description of Capecitabine

Capecitabine: A fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand. (NCI04)
Source: Diseases Database

Capecitabine: Related Topics

These medical condition or symptom topics may be relevant to medical information for Capecitabine:

External links related to: Capecitabine

Source: Diseases Database

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