Cardiac glycosides

Introduction: Cardiac glycosides

Description of Cardiac glycosides

Cardiac glycosides: Substances obtained from species of Digitalis, Strophanthus, and other plants that contain specific steroid glycosides or their semisynthetic derivatives and used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the Na(+)-K(+)-exchanging ATPase and they are often used in cell biological studies for that purpose.
Source: Diseases Database

Cardiac glycosides: Cyclopentanophenanthrenes with a 5- or 6-membered lactone ring attached at the 17-position and SUGARS attached at the 3-position. Plants they come from have long been used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the NA(+)-K(+)-EXCHANGING ATPASE and they are often used in cell biological studies for that purpose.
Source: MeSH 2007

Cardiac glycosides: Related Topics

These medical condition or symptom topics may be relevant to medical information for Cardiac glycosides:

• Cardiac
• Cardiac symptoms (2927 causes)
• Cardiac disease
• Cardiac disorder
• Generic
• Term
• Number
• Capacity

Terms associated with Cardiac glycosides:

Terms Similar to Cardiac glycosides:

• Digitalis glycosides

Source: Diseases Database

• Cardiotonic Steroids

Source - MeSH 2007

More specific terms for Cardiac glycosides:

• Bufanolides
• Cardenolides
• Digitalis Glycosides
• Proscillaridin
• Strophanthins

Source - MeSH 2007

Broader terms for Cardiac glycosides

• Cardanolides
• Glycosides

Source - MeSH 2007

Hierarchical classifications of Cardiac glycosides

The following list attempts to classify Cardiac glycosides into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Polycyclic Compounds
  • Steroids
    • Cardanolides
      • Cardiac Glycosides

MeSH 2007 Hierarchy

• Carbohydrates
  • Glycosides
    • Cardiac Glycosides

External links related to: Cardiac glycosides

• Digitalis for treatment of congestive heart failure in patients in sinus rhythm (Cochrane Review)

Source: Diseases Database

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