Carmustine

Introduction: Carmustine

Description of Carmustine

Carmustine: An anticancer drug that belongs to the family of drugs called alkylating agents.
Source: National Institute of Health

Carmustine: An antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. (NCI04)
Source: Diseases Database

Carmustine: cell cycle phase nonspecific alkylating antineoplastic agent used in the treatment of brain tumors and various other cancers.
Source: CRISP

Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed).
Source: MeSH 2007

Carmustine: Related Topics

These medical condition or symptom topics may be relevant to medical information for Carmustine:

• Antineoplastic
• Agent
• SYN
• BCNU

Terms associated with Carmustine:

Terms Similar to Carmustine:

• BCNU
• bis-chloronitrosourea

Source: Diseases Database

• BCNU

Source - MeSH 2007

Broader terms for Carmustine

• Nitrosourea Compounds

Source - MeSH 2007

• antineoplastic
• nitrosourea

Source - CRISP

The term Carmustine can be used for:

• BCNU (bis chloroethylnitrosourea)
• bis chloroethylnitrosourea

Source: CRISP

The description of Carmustine may also be used for the following terms:

• BCNU
• chloroethylnitrosourea

Source: CRISP

Hierarchical classifications of Carmustine

The following list attempts to classify Carmustine into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Organic Chemicals
  • Nitroso Compounds
    • Nitrosourea Compounds
      • Carmustine

MeSH 2007 Hierarchy

• Organic Chemicals
  • Urea
    • Nitrosourea Compounds
      • Carmustine

External links related to: Carmustine

• BiCNU Injection , SPC from the eMC
• CancerSourceMD.Com Drug Guide
• Bicnu Online, Description, Chemistry, Ingredients - Carmustine - RxList Monographs

Source: Diseases Database

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Medical dictionaries:

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