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Colesevelam hydrochloride: A polymeric synthetic polyallylamine derivative cross-linked with epichlorohydrin, Colesevelam Hydrochloride is a non-absorbed, water-insoluble, lipid-lowering, hydrophilic agent that binds intestinal bile acids and impedes their reabsorption. Used alone or with other medications, Colesevelam increases cholesterol metabolism and decreases its plasma concentration. (NCI04)
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