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Dictionary » Cyclin-Dependent Kinase Inhibitor p27
 

Cyclin-Dependent Kinase Inhibitor p27

Introduction: Cyclin-Dependent Kinase Inhibitor p27

Description of Cyclin-Dependent Kinase Inhibitor p27

Cyclin-Dependent Kinase Inhibitor p27: A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and CYCLIN-DEPENDENT KINASES during the CELL CYCLE. It interacts with active CYCLIN D complexed to CYCLIN-DEPENDENT KINASE 4 in proliferating cells, while in arrested cells it binds and inhibits CYCLIN E complexed to CYCLIN-DEPENDENT KINASE 2.
Source: MeSH 2007

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