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Cytochrome b5 reductase

Introduction: Cytochrome b5 reductase

Description of Cytochrome b5 reductase

Cytochrome b5 reductase: EC 1.6.2.2.
Source: CRISP

Cytochrome b5 reductase: A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane, where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA.
Source: MeSH 2007

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Source - CRISP

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Source: CRISP

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