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Dictionary » Diethyldithiocarbamate


Introduction: Diethyldithiocarbamate

Description of Diethyldithiocarbamate

Diethyldithiocarbamate: A sulfhydryl-containing carbamate that is the primary in vivo metabolite of disulfiram. Diethyldithiocarbamate chelates zinc, thereby inhibiting metalloproteinases, thereby preventing the degradation of the extracellular matrix and inhibiting an initial step in cancer metastasis and angiogenesis. A known inhibitor of superoxide dismutase, this agent can either potentiate or protect against cell oxidative damage caused by ionizing radiation, depending on the time of administration. (NCI04)
Source: Diseases Database

Diethyldithiocarbamate: Related Topics

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  • Other symptoms referable to joint of multiple sites
  • Other symptoms referable to joint of other specified sites
  • Other symptoms referable to joint of pelvic region and thigh
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  • Other symptoms referable to joint, site unspecified
  • Other symptoms referable to lower leg joint
  • Other symptoms referable to upper arm joint
  • Other syndromes affecting cervical region
  • Other synovitis and tenosynovitis
  • Other systemic agents, not elsewhere classified, causing adverse effects in therapeutic use

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