Diethyldithiocarbamate

Introduction: Diethyldithiocarbamate

Description of Diethyldithiocarbamate

Diethyldithiocarbamate: A sulfhydryl-containing carbamate that is the primary in vivo metabolite of disulfiram. Diethyldithiocarbamate chelates zinc, thereby inhibiting metalloproteinases, thereby preventing the degradation of the extracellular matrix and inhibiting an initial step in cancer metastasis and angiogenesis. A known inhibitor of superoxide dismutase, this agent can either potentiate or protect against cell oxidative damage caused by ionizing radiation, depending on the time of administration. (NCI04)
Source: Diseases Database

Diethyldithiocarbamate: Related Topics

These medical condition or symptom topics may be relevant to medical information for Diethyldithiocarbamate:

• Carbamate
• Primary
• Primary disease
• Metabolite
• Disulfiram
• Zinc
• Degradation
• Extracellular
• Matrix
• Step

Terms associated with Diethyldithiocarbamate:

Terms Similar to Diethyldithiocarbamate:

• Dithiocarb
• Ditiocarb
• Thiocarb

Source: Diseases Database

External links related to: Diethyldithiocarbamate

• Sodium diethyldithiocarbamate (CASRN 148-18-5), IRIS, Environmental Protection Agency

Source: Diseases Database

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