Diffuse sclerosis of Schilder

Introduction: Diffuse sclerosis of Schilder

Description of Diffuse sclerosis of Schilder

Diffuse sclerosis of Schilder: A rare central nervous system demyelinating condition affecting children and young adults. Pathologic findings include a large, sharply defined, asymmetric focus of myelin destruction that may involve an entire lobe or cerebral hemisphere. The clinical course tends to be progressive and includes dementia, cortical blindness, cortical deafness, spastic hemiplegia, and pseudobulbar palsy. Concentric sclerosis of Balo is differentiated from diffuse cerebral sclerosis of Schilder by the pathologic finding of alternating bands of destruction and preservation of myelin in concentric rings. Alpers' Syndrome refers to a heterogeneous group of diseases that feature progressive cerebral deterioration and liver disease. (From Adams et al., Principles of Neurology, 6th ed, p914; Dev Neurosci 1991;13(4-5):267-73)
Source: Diseases Database

Diffuse sclerosis of Schilder: Related Topics

These medical condition or symptom topics may be relevant to medical information for Diffuse sclerosis of Schilder:

• Diffuse sclerosis
• Diffuse
• Sclerosis
• Schilder
• Schilder disease
• Nervous (73 causes)
• System
• Condition
• Young

Terms associated with Diffuse sclerosis of Schilder:

Terms Similar to Diffuse sclerosis of Schilder:

• Balo's concentric sclerosis
• Encephalitis periaxalis diffusa
• Myelinoclastic diffuse sclerosis
• Schilder's disease

Source: Diseases Database

External links related to: Diffuse sclerosis of Schilder

• Schilder syndrome
• Schilder's disease (www.whonamedit.com)
• OMIM - SUDANOPHILIC CEREBRAL SCLEROSIS
• eMedicine - Diffuse Sclerosis : Article by Robert S Rust, Jr, MD
• Schilder's Disease Information Page: National Institute of Neurological Disorders and Stroke (NINDS)

Source: Diseases Database

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