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Efavirenz: A synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral properties. Efavirenz binds directly to the human immunodeficiency virus type 1 (HIV-1) RT, an RNA-dependent DNA polymerase, blocking its function in viral DNA replication. In combination with other antiretroviral drugs, this agent has been shown to significantly reduce HIV viral loads, therefore retarding or preventing damage to the immune system, and reducing the risk of developing AIDS. Efavirenz induces activity of the cytochrome P450 system, thereby accelerating its own metabolism. (NCI04)
Source: Diseases Database
Efavirenz: antiHIV 1 agent; reverse transcriptase inhibitor; 6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1, 4-dihydro-2H-3,1-benzoxazin-2-one.
Source: CRISP
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Source: CRISP
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Source: Diseases Database
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