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Fenretinide: An orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis-associated growth factors and their receptors and exhibits retinoid receptor-independent apoptotic properties.(NCI04)
Source: Diseases Database
Fenretinide: N-(4-hydroxyphenyl)retinamide; a synthetic retinoid used orally as a chemopreventive agent against prostate cancer in men and in women at risk of developing breast cancer; also effective as an antineoplastic agent.
Fenretinide: A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Source: MeSH 2007
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Source - CRISP
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