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Gemcitabine

Introduction: Gemcitabine

Description of Gemcitabine

Gemcitabine: An antimetabolite analog of the nucleoside pyrimidine with antineoplastic activity. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. (NCI04)
Source: Diseases Database

Gemcitabine: antimetabolite used in the treatment of pancreatic, lung, and other cancers.
Source: CRISP

Gemcitabine: Related Topics

These medical condition or symptom topics may be relevant to medical information for Gemcitabine:

Terms associated with Gemcitabine:

Terms Similar to Gemcitabine:

Source - CRISP

Broader terms for Gemcitabine

Source - CRISP

The description of Gemcitabine may also be used for the following terms:

Source: CRISP

External links related to: Gemcitabine

Source: Diseases Database

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