Helix-Turn-Helix Motifs

Introduction: Helix-Turn-Helix Motifs

Description of Helix-Turn-Helix Motifs

Helix-Turn-Helix Motifs: The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9).
Source: MeSH 2007

Helix-Turn-Helix Motifs: Related Topics

These medical condition or symptom topics may be relevant to medical information for Helix-Turn-Helix Motifs:

• Helix-Turn-Helix
• Helix
• Turn

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