IL10

Introduction: IL10

Description of IL10

IL10: Expressed primarily in monocytes and less in lymphocytes by human IL10 Gene, Interleukin-10 is a cytokine with pleiotropic effects in immunoregulation and inflammation. It down-regulates expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Studies in mice suggest that this cytokine as an essential immunoregulator in the intestinal tract. (From LocusLink)
Source: Diseases Database

IL10: Related Topics

These medical condition or symptom topics may be relevant to medical information for IL10:

• Monocytes
• Lymphocytes
• Human
• Gene
• Cytokine
• Pleiotropic
• Immunoregulation
• Inflammation
• Down
• Down syndrome

Terms associated with IL10:

Terms Similar to IL10:

• Interleukin 10
• Cytokine synthesis inhibiting factor

Source: Diseases Database

For a description of IL10, see:

• interleukin 10

Source: CRISP

External links related to: IL10

• OMIM - INTERLEUKIN 10; IL10

Source: Diseases Database

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Oromandibulo-auricular syndrome

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