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Isaacs syndrome (medical condition): A rare disorder where muscles suffer from stiffness and cramping,...more »
Isaacs syndrome: A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491).
Source: MeSH 2007
Isaacs syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Isaacs syndrome, or a subtype of Isaacs syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Isaacs syndrome: Isaacs syndrome is listed as a type of (or associated with) the following medical conditions in our database:
These medical disease topics may be related to Isaacs syndrome:
Source - NIH
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