Lomustine

Introduction: Lomustine

Description of Lomustine

Lomustine: An anticancer drug that belongs to the family of drugs called alkylating agents.
Source: National Institute of Health

Lomustine: an antineoplastic drug often used to treat brain tumors or Hodgkin's disease.
Source: WordNet 2.1

Lomustine: A nitrosourea with antineoplastic activity. Lomustine alkylates and crosslinks DNA, thereby inhibiting DNA and RNA synthesis. This agent also carbamoylates DNA and proteins, resulting in inhibition of DNA and RNA synthesis and disruption of RNA processing. Lomustine is lipophilic and crosses the blood-brain barrier. (NCI04)
Source: Diseases Database

Lomustine: cytotoxic alkylating agent of the nitrosourea group used as an antineoplastic.
Source: CRISP

Lomustine: An alkylating agent of value against both hematologic malignancies and solid tumors.
Source: MeSH 2007

Lomustine: Related Topics

These medical condition or symptom topics may be relevant to medical information for Lomustine:

• Antineoplastic
• Agent
• SYN
• CCNU

Terms associated with Lomustine:

Terms Similar to Lomustine:

• CCNU

Source: Diseases Database

• CCNU

Source - MeSH 2007

More specific terms for Lomustine:

• Semustine

Source - MeSH 2007

Broader terms for Lomustine

• Nitrosourea Compounds

Source - MeSH 2007

• antineoplastic
• nitrosourea

Source - CRISP

• antineoplastic
• antineoplastic drug
• cancer drug

Source - WordNet 2.1

The term Lomustine can be used for:

• CCNU (cyclohexylchloroethylnitrosourea)
• cyclohexylchloroethylnitrosourea

Source: CRISP

The description of Lomustine may also be used for the following terms:

• CCNU
• chloroethylnitrosourea

Source: CRISP

Hierarchical classifications of Lomustine

The following list attempts to classify Lomustine into categories where each line is subset of the next.

WordNet 2.1

• antineoplastic,antineoplastic drug,cancer drug
• cytotoxic drug
• medicament,medication,medicinal drug,medicine
• drug
• agent
• causal agency,causal agent,cause
• entity

Source: WordNet 2.1

MeSH 2007 Hierarchy:

• Organic Chemicals
  • Nitroso Compounds
    • Nitrosourea Compounds
      • Lomustine

MeSH 2007 Hierarchy

• Organic Chemicals
  • Urea
    • Nitrosourea Compounds
      • Lomustine

External links related to: Lomustine

• Lomustine "medac" 40 mg , SPC from the eMC
• Chemotherapy versus best supportive care for extensive small cell lung cancer (Cochrane Review)
• Ceenu Online, Description, Chemistry, Ingredients - Lomustine - RxList Monographs
• CancerSourceMD.Com Drug Guide
• MDAdvice.com - Health Library - Prescription & Non-Prescription Drugs - LOMUSTINE

Source: Diseases Database

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Medical dictionaries:

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• Medical Acronymns/Abbreviations

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