MEN type 1

Introduction: MEN type 1

Description of MEN type 1

MEN type 1: The MEN1 gene is a cloned tumor suppressor gene for Multiple Endocrine Neoplasia, a predisposition for endocrine tumors and carcinoid tumors. The gene encodes the tumor suppressor protein MEN1, which regulates transcription through direct interaction with, and inhibition of, transcription factor JunD. Menin also interacts with SMAD3 and appears to be required for SMAD3/4-DNA binding at transcriptional regulatory sites. The human gene is located at 11q13.
Source: Diseases Database

MEN type 1: Related Topics

These medical condition or symptom topics may be relevant to medical information for MEN type 1:

• Type
• MEN1
• Gene
• Tumor
• Tumor pain
• Suppressor
• Endocrine
• Endocrine symptoms (217 causes)
• Endocrine disease
• Endocrine disorder (43 causes)

Terms associated with MEN type 1:

Terms Similar to MEN type 1:

• Wermer's syndrome
• Multiple endocrine neoplasia type 1

Source: Diseases Database

External links related to: MEN type 1

• OMIM - MULTIPLE ENDOCRINE NEOPLASIA, TYPE I; MEN1
• MEN-1 (Wermer) syndrome
• eMedicine - Wermer Syndrome (MEN Type 1) : Article by Klaus Radebold, MD, PhD
• Wermer's syndrome (www.whonamedit.com)
• Multiple endocrine neoplasia type 1 - Genetics Home Reference
• eMedicine - Multiple Endocrine Neoplasia Type 1 : Article by Thomas N Darling, MD, PhD
• GeneReviews: Multiple Endocrine Neoplasia Type 1

Source: Diseases Database

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• Medical Acronymns/Abbreviations

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