Methylenetetrahydrofolate Dehydrogenase (NADP)

Introduction: Methylenetetrahydrofolate Dehydrogenase (NADP)

Description of Methylenetetrahydrofolate Dehydrogenase (NADP)

Methylenetetrahydrofolate Dehydrogenase (NADP): An NADP-dependent oxidoreductase that catalyses the conversion of 5,10-methyleneterahydrofolate to 5,10-methenyl-tetrahydrofolate. In higher eukaryotes a trifunctional enzyme exists with additional METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE and FORMATE-TETRAHYDROFOLATE LIGASE activity. The enzyme plays an important role in the synthesis of 5-methyltetrahydrofolate, the methyl donor for the VITAMIN B12-dependent remethylation of HOMOCYSTEINE to METHIONINE via METHIONINE SYNTHETASE.
Source: MeSH 2007

Methylenetetrahydrofolate Dehydrogenase (NADP): Related Topics

These medical condition or symptom topics may be relevant to medical information for Methylenetetrahydrofolate Dehydrogenase (NADP):

• Methylenetetrahydrofolate Dehydrogenase
• Dehydrogenase
• NADP

Terms associated with Methylenetetrahydrofolate Dehydrogenase (NADP):

Terms Similar to Methylenetetrahydrofolate Dehydrogenase (NADP):

• Methylenetetrahydrofolate Dehydrogenase (NADP+)

Source - MeSH 2007

Related Topics

• Formate-Tetrahydrofolate Ligase
• Methenyltetrahydrofolate Cyclohydrolase

Source - MeSH 2007

Broader terms for Methylenetetrahydrofolate Dehydrogenase (NADP)

• Oxidoreductases Acting on CH-NH Group Donors

Source - MeSH 2007

Hierarchical classifications of Methylenetetrahydrofolate Dehydrogenase (NADP)

The following list attempts to classify Methylenetetrahydrofolate Dehydrogenase (NADP) into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Enzymes and Coenzymes
  • Enzymes
    • Oxidoreductases
      • Oxidoreductases Acting on CH-NH Group Donors
        • Methylenetetrahydrofolate Dehydrogenase (NADP)

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