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Dictionary » Phosphofructokinase-1, Muscle Type
 

Phosphofructokinase-1, Muscle Type

Introduction: Phosphofructokinase-1, Muscle Type

Description of Phosphofructokinase-1, Muscle Type

Phosphofructokinase-1, Muscle Type: An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans$, PHOSPHOFRUCTOKINASE-$1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.
Source: MeSH 2007

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