Raltitrexed

Introduction: Raltitrexed

Description of Raltitrexed

Raltitrexed: A quinazoline folate analogue with antineoplastic activity. After transport into cells via the reduced folate carrier, raltitrexed undergoes intracellular polyglutamation and blocks the folate-binding site of thymidylate synthase, thereby inhibiting tetrahydrofolate activity and DNA replication and repair and resulting in cytotoxicity. (NCI04)
Source: Diseases Database

Raltitrexed: Related Topics

These medical condition or symptom topics may be relevant to medical information for Raltitrexed:

• Quinazoline
• Folate
• Folate symptoms (15 causes)
• Analogue
• Antineoplastic
• Transport
• Via
• Carrier

Terms associated with Raltitrexed:

Terms Similar to Raltitrexed:

• Ralitrexed

Source: Diseases Database

External links related to: Raltitrexed

• Colorectal cancer (advanced) - irinotecan, oxaliplatin & raltitrexed (No. 33)
• Tomudex , SPC from the eMC
• Colorectal cancer (advanced) - irinotecan, oxaliplatin and raltitrexed (review) (No. 93)
• CancerSourceMD.Com Drug Guide

Source: Diseases Database

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