Razoxane

Introduction: Razoxane

Description of Razoxane

Razoxane: A bis-dioxopiperazine and a derivative of the chelating agent EDTA with antineoplastic activity. Razoxane inhibits the enzyme topoisomerase II without inducing DNA strand breaks, thereby inhibiting DNA synthesis and inducing cytotoxicity. Although its mechanism is unknown, this agent exhibits anti-angiogenic activity. (NCI04)
Source: Diseases Database

Razoxane: An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex.
Source: MeSH 2007

Razoxane: Related Topics

These medical condition or symptom topics may be relevant to medical information for Razoxane:

• Bis
• Derivative
• Agent
• EDTA
• Antineoplastic
• Enzyme
• Topoisomerase
• DNA
• Strand
• Synthesis

Terms associated with Razoxane:

Terms Similar to Razoxane:

• Dexrazoxane

Source - MeSH 2007

Broader terms for Razoxane

• Piperazines

Source - MeSH 2007

Hierarchical classifications of Razoxane

The following list attempts to classify Razoxane into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

• Heterocyclic Compounds
  • Heterocyclic Compounds, 1-Ring
    • Piperazines
      • Razoxane

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More Medical Dictionary Topics

Iatrochemical

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