Rosiglitazone

Introduction: Rosiglitazone

Description of Rosiglitazone

Rosiglitazone: An orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. Rosiglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation.(NCI04)
Source: Diseases Database

Rosiglitazone: peroxisome proliferator activated receptor agonist; reduces lipid availability; improves insulin action and glucoregulation.
Source: CRISP

Rosiglitazone: Related Topics

These medical condition or symptom topics may be relevant to medical information for Rosiglitazone:

• Thiazolidinedione
• Antidiabetic
• Potential
• Antineoplastic
• Peroxisome
• Receptor
• PPAR
• Ligand
• Transcription
• Factor

Terms associated with Rosiglitazone:

Broader terms for Rosiglitazone

• hypoglycemic agent
• thiazole

Source - CRISP

The term Rosiglitazone can be used for:

• BRL49653

Source: CRISP

External links related to: Rosiglitazone

• Avandia 4mg & 8mg Tablets , SPC from the eMC
• Diabetes (type 2) - glitazones (review) (No. 63)
• Avandia Online, Description, Chemistry, Ingredients - Rosiglitazone Maleate - RxList Monographs

Source: Diseases Database

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