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Dictionary » Simvastatin


Introduction: Simvastatin

Description of Simvastatin

Simvastatin (medical condition): There is evidence to indicate that exposure to Simvastatin during pregnancy...more »

See also:

Simvastatin -- Teratogenic Agent:
  »Introduction: Simvastatin -- Teratogenic Agent
  »Symptoms of Simvastatin -- Teratogenic Agent

Simvastatin: an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks.
Source: WordNet 2.1

Simvastatin: A lipid-lowering agent derived synthetically from a fermentation product of the fungus Aspergillus terreus. Hydrolyzed in vivo to an active metabolite, simvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. (NCI04)
Source: Diseases Database

Simvastatin: a derivative of lovastatin and inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG coA reductase), a rate limiting enzyme in the biosynthesis of cholesterol.
Source: CRISP

Simvastatin: A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.
Source: MeSH 2007

Simvastatin: Related Topics

These medical condition or symptom topics may be relevant to medical information for Simvastatin:

Simvastatin as a Disease

Simvastatin: Another name for Simvastatin -- Teratogenic Agent (or close medical condition association).
  »Introduction: Simvastatin -- Teratogenic Agent
  »Symptoms of Simvastatin -- Teratogenic Agent

Simvastatin: Related Diseases

Simvastatin: Simvastatin is listed as a type of (or associated with) the following medical conditions in our database:

Symptoms of Simvastatin (Simvastatin -- Teratogenic Agent)

Some of the symptoms of Simvastatin incude:

Terms associated with Simvastatin:

Terms Similar to Simvastatin:

Source - WordNet 2.1

Broader terms for Simvastatin

Source - CRISP

Source - WordNet 2.1

The term Simvastatin can be used for:

Source: CRISP

Hierarchical classifications of Simvastatin

The following list attempts to classify Simvastatin into categories where each line is subset of the next.

WordNet 2.1

  • lipid-lowering medication,lipid-lowering medicine,statin,statin drug
  • medicament,medication,medicinal drug,medicine
  • drug
  • agent
  • causal agency,causal agent,cause
  • entity

Source: WordNet 2.1

External links related to: Simvastatin

Source: Diseases Database

Interesting Medical Articles:

Medical dictionaries:

More Medical Dictionary Topics

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  • Alcohol addiction
  • Alcohol affecting fetus or newborn via placenta or breast milk
  • Alcohol Amnestic Disorder
  • Alcohol and drug rehabilitation and detoxification
  • Alcohol antenatal infection
  • Alcohol ataxia
  • Alcohol binging
  • Alcohol craving
  • Alcohol dehydrogenase
  • Alcohol dehydrogenase (acceptor)
  • Alcohol dehydrogenase (NADP+)
  • Alcohol dependency
  • Alcohol Deterrents

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