Stavudine

Introduction: Stavudine

Description of Stavudine

Stavudine: A synthetic nucleoside, analog of didehydro-3-deoxythymidine with potent antiretroviral activity. In vivo, stavudine is phosphorylated by cellular kinases to the active metabolite stavudine triphosphate; this metabolite inhibits the activity of HIV reverse transcriptase both by competing with the natural substrate deoxythymidine triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack the essential 3'-OH group). (NCI04)
Source: Diseases Database

Stavudine: nucleoside analog; used as an antiviral agent.
Source: CRISP

Stavudine: A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Source: MeSH 2007

Stavudine: Related Topics

These medical condition or symptom topics may be relevant to medical information for Stavudine:

• Synthetic
• Nucleoside
• Analog
• Potent
• Cellular
• Metabolite
• HIV
• HIV disease (8 causes)
• Transcriptase
• Incorporation

Terms associated with Stavudine:

Terms Similar to Stavudine:

• d4T

Source: Diseases Database

• zerit

Source - CRISP

Broader terms for Stavudine

• 2'3' dideoxynucleoside

Source - CRISP

The term Stavudine can be used for:

• 2'3' didehydro 3' deoxythymidine
• 2'3' didehydrodeoxythymidine
• d4T

Source: CRISP

Other terms that may be related to Stavudine:

• antiAIDS agent

Source: CRISP

External links related to: Stavudine

• Zerit 200 mg Powder for Oral Solution , SPC from the eMC
• MedDet
• RxMed: Pharmaceutical Information - ZERIT
• Zerit (stavudine; d4T): a complete guide from AIDSmeds.com
• Zerit 15 mg, 20 mg, 30 mg and 40 mg Hard Capsules , SPC from the eMC
• Zerit Online, Description, Chemistry, Ingredients - Stavudine - RxList Monographs

Source: Diseases Database

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Medical dictionaries:

• Medical dictionary,
• Medical Acronymns/Abbreviations

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