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Dictionary » TPA


Introduction: TPA

Description of TPA

TPA: A secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. (from LocusLink)
Source: Diseases Database

TPA: Related Topics

These medical condition or symptom topics may be relevant to medical information for TPA:

Terms associated with TPA:

Terms Similar to TPA:

Source: Diseases Database

For a description of TPA, see:

Source: CRISP

External links related to: TPA

Source: Diseases Database

Interesting Medical Articles:

Medical dictionaries:

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