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Dictionary » TPA


Introduction: TPA

Description of TPA

TPA: A secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. (from LocusLink)
Source: Diseases Database

TPA: Related Topics

These medical condition or symptom topics may be relevant to medical information for TPA:

Terms associated with TPA:

Terms Similar to TPA:

Source: Diseases Database

For a description of TPA, see:

Source: CRISP

External links related to: TPA

Source: Diseases Database

Interesting Medical Articles:

Medical dictionaries:

More Medical Dictionary Topics

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  • Pterygium unguis
  • Pterygium universale
  • Pterygium, unspecified
  • Pterygo-
  • Pterygoid
  • Pterygoid branch of posterior deep temporal artery
  • Pterygoid branches of maxillary artery
  • Pterygoid buttress
  • Pterygoid canal
  • Pterygoid chest
  • Pterygoid depression

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