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Transforming growth factor: any of several proteins secreted by transformed cells and stimulating growth of normal cells; transforming growth factor alpha binds the epidermal growth factor receptor and also stimulates growth of microvascular endothelial cells; transforming growth factor beta exists as several subtypes; all occur in hematopoietic tissue, stimulate wound healing, and in vitro are antagonists of lymphopoiesis and myelopoiesis.
Source: CRISP
Transforming growth factor: Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.
Source: MeSH 2007
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Source - MeSH 2007
Source - CRISP
Source - MeSH 2007
Source - CRISP
Source: CRISP
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