Vascular endothelial growth factor

Introduction: Vascular endothelial growth factor

Description of Vascular endothelial growth factor

Vascular endothelial growth factor: The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
Source: Diseases Database

Vascular endothelial growth factor: heparin binding growth factor that regulates endothelial cell proliferation; also acts as an angiogenic factor.
Source: CRISP

Vascular endothelial growth factor: A family of angiogenic proteins that are closely-related to VASCULAR ENDOTHELIAL GROWTH FACTOR A. They play an important role in the growth and differentiation of vascular as well as lymphatic endothelial cells.
Source: MeSH 2007