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Dictionary » Vascular Endothelial Growth Factor Receptor-1
 

Vascular Endothelial Growth Factor Receptor-1

Introduction: Vascular Endothelial Growth Factor Receptor-1

Description of Vascular Endothelial Growth Factor Receptor-1

Vascular Endothelial Growth Factor Receptor-1: A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
Source: MeSH 2007

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