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Neonatal lupus

Neonatal lupus: Introduction

Neonatal lupus: Neonatal lupus is a rare form of lupus affecting newborn babies of women with SLE or certain other immune system disorders. ... more about Neonatal lupus.

Neonatal lupus: Neonatal lupus erythematosus (NLE) is a rare disorder caused by the transplacental passage of maternal autoantibodies. The most common clinical manifestations are cardiac, dermatologic, and hepatic. Some infants may also have hematologic abnormalities. More detailed information about the symptoms, causes, and treatments of Neonatal lupus is available below.

Symptoms of Neonatal lupus

Treatments for Neonatal lupus

  • The type of treatment and the long-term prognosis for neonates with cardiac rhythm and conduction disturbances depends on the presence of underlying congenital heart abnormalities
  • Treatment of skin lesions includes mild steroids and, possibly, laser treatment for residual telangiectasia
  • Photoprotection is highly desirable because solar exposure may precipitate skin lesions
  • In severe cases, surgical implantation of a pacemaker, along with the correction of structural abnormalities in the heart, may be necessary
  • more treatments...»

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Neonatal lupus: Complications

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Causes of Neonatal lupus

  • The mother produces autoantibodies against Ro (SSA), La (SSB), and/or U1-RNP, and they are passively transported across the placenta. The presence of maternal anti-SSA/Ro and anti-SSB/La antibodies increases the risk of bearing infants with NLE
  • Mothers of patients with NLE may have defined or undifferentiated autoimmune disorders, such as SLE, SS, UAS, or RA
  • more causes...»

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Disease Topics Related To Neonatal lupus

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Neonatal lupus: Undiagnosed Conditions

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Misdiagnosis and Neonatal lupus

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Neonatal lupus: Rare Types

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Article Excerpts about Neonatal lupus

Handout on Health Systemic Lupus Erythematosus: NIAMS (Excerpt)

Neonatal lupus is a rare form of lupus affecting newborn babies of women with SLE or certain other immune system disorders. At birth, the babies have a skin rash, liver abnormalities, or low blood counts, which entirely go away over several months. However, babies with neonatal lupus may have a serious heart defect. Physicians can now identify most at-risk mothers, allowing for prompt treatment of the infant at or before birth. Neonatal lupus is very rare, and most infants of mothers with SLE are entirely healthy. (Source: excerpt from Handout on Health Systemic Lupus Erythematosus: NIAMS)

Handout on Health Systemic Lupus Erythematosus: NIAMS (Excerpt)

Physicians can now identify most at-risk mothers, allowing for prompt treatment of the infant at or before birth. Neonatal lupus is very rare, and most infants of mothers with SLE are entirely healthy. (Source: excerpt from Handout on Health Systemic Lupus Erythematosus: NIAMS)

Lupus Fact Sheet: NWHIC (Excerpt)

Neonatal lupus can affect some newborn babies of women with SLE or certain other immune system disorders. Babies with neonatal lupus may have a serious heart defect. Other affected babies may have a skin rash, liver abnormalities, or low blood counts. Neonatal lupus is very rare, and most infants of mothers with SLE are entirely healthy. (Source: excerpt from Lupus Fact Sheet: NWHIC)

 

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