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Treatments for Neurosyphilis

Treatment List for Neurosyphilis

The list of treatments mentioned in various sources for Neurosyphilis includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

  • Late syphilis (Tertiary syphilis, neurosyphilis, syphilis >1yr or unknown duration)
  • Asymptomatic
    • Benzathine penicillin IM weekly for 3 doses, or procaine penicillin daily for 15 days
    • Repetition of blood tests - to ensure treatment successful; see tests for syphilis
    • Contact tracing and treatment of partners
  • Symptomatic
    • IV Crystalline penicillin for 10-14 days or IM procaine penicillin plus probenecid daily
    • In the case of penicillin allergy, testing should be undertaken if allergy is proven alternatives such as doxycycline, erythromycin and ceftriaxone may be used

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Hospitals & Medical Clinics: Neurosyphilis

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