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Early studies found that single doses of the anti-retroviral drug nevirapine in HIV-positive pregnant women helped prevent HIV transmission in about 50% of births. Reporting problems and possible incorrect administration of the drug during human trials conducted by NIH led to a suspension of the study while it was being reviewed and altered. One woman had received multiple doses of the drug and allegedly died from liver damage soon after delivering her baby who was free of HIV. Side effects of the drug include liver damage or rashes if taken long term or in multiple doses. It is claimed that doctors should have noticed that the pregnant woman's liver was failing as early as two weeks prior to the birth. Corrective measures could possibly have saved her life. The woman's family is seeking legal action to find out exactly what happened. The family also claims that the woman was not made fully aware of the risks of liver damage. The NIH is defending the benefits of nevirapine.
Source: summary of medical news story as reported by Medical News Today
About: Anti-retroviral drug trial may have led to pregnant woman's death
Date: 17 December 2004
Source: Medical News Today
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