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Tamoxifen is currently used to treat hormone receptor-positive breast cancers as well as a preventative measure in those at high risk of the disease. The drugs efficacy varies amongst women. SSRI's are frequently prescribed in women taking tamoxifen in order to treat hot flushes associated with the drug. Researchers have found that some SSRI's can alter the activity of tamoxifen. By carefully analyzing how SSRI's interact with certain enzymes in different women, it may be possible to determine which women will benefit more from tamoxifen in combination with which SSRI.
Source: summary of medical news story as reported by Medical News Today
About: Antidepressants affect tamoxifen activity in some women
Date: 5 January 2005
Source: Medical News Today
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