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Researchers have found that patients who use rofecoxib faced three times the risk of a myocardial infarction compared to those on celecoxib. Nonselective nonaspirin NSAIDs did not seem to increase the risk of a myocardial infarction. Researchers want more studies down on the effects of the whole range of COX-2 inhibitors and believe that COX-2 inhibitors shouldn't be used in patients at risk of cardiovascular disease or gastrointestinal toxicity unless absolutely necessary. These researcher claim that nonselective nonaspirin NSAIDs are a safer option.
Source: summary of medical news story as reported by Medical News Today
About: COX-2 inhibitors need further analysis to determine the range of side effects
Date: 8 December 2004
Source: Medical News Today
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