Paroxysmal Nocturnal Hemoglobinuria: The distinct and rather peculiar characteristics of paroxysmal nocturnal hemoglobinuria (PNH) have puzzled hematologists for more than a century. PNH is characterized by a ... more about Paroxysmal Nocturnal Hemoglobinuria.
Paroxysmal Nocturnal Hemoglobinuria: A condition which is characterized by the occurrence of hemoglobinuria at night without any identifiable cause. More detailed information about the symptoms, causes, and treatments of Paroxysmal Nocturnal Hemoglobinuria is available below.
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The distinct and rather peculiar characteristics of paroxysmal nocturnal hemoglobinuria (PNH) have puzzled hematologists for more than a century. PNH is characterized by a decreased number of red blood cells (anemia), and the presence of blood in the urine (hemoglobinuria) and plasma (hemoglobinemia), which is evident after sleeping. (Source: Genes and Disease by the National Center for Biotechnology)
Paroxysmal Nocturnal Hemoglobinuria is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Paroxysmal Nocturnal Hemoglobinuria, or a subtype of Paroxysmal Nocturnal Hemoglobinuria,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Paroxysmal Nocturnal Hemoglobinuria as a "rare disease".
Source - Orphanet
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