POEMS syndrome: A very rare disorder that has widespread effects on the body: P - polyneuropathy, O - organopathy, E - endocrinopathy, M - monoclonal gammopathy, S - skin changes. More detailed information about the symptoms, causes, and treatments of POEMS syndrome is available below.
See full list of 29 symptoms of POEMS syndrome
Read more about Deaths and POEMS syndrome.
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Read more about causes of POEMS syndrome.
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Types of POEMS syndrome
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A multisystemic disorder characterized by a sensorimotor polyneuropathy (POLYNEUROPATHIES), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. Other clinical features which may be present include EDEMA; CACHEXIA; microangiopathic glomerulopathy; pulmonary hypertension (HYPERTENSION, PULMONARY); cutaneous necrosis; THROMBOCYTOSIS; and POLYCYTHEMIA. This disorder is frequently associated with osteosclerotic myeloma. (From Adams et al., Principles of Neurology, 6th ed, p1335; Rev Med Interne 1997;18(7):553-62) - (Source - Diseases Database)
POEMS syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that POEMS syndrome, or a subtype of POEMS syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list POEMS syndrome as a "rare disease".
Source - Orphanet
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