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Causes of Porphyria

Causes of Porphyria

Porphyria is caused by a mutation in one of several different genes. The mutations are passed down through families. Environmental and lifestyle factors exacerbate certain types of porphyria.

Porphyria: Related Medical Conditions

To research the causes of Porphyria, consider researching the causes of these these diseases that may be similar, or associated with Porphyria:

Porphyria: Causes and Types

Causes of Broader Categories of Porphyria: Review the causal information about the various more general categories of medical conditions:

Porphyria as a symptom:

Conditions listing Porphyria as a symptom may also be potential underlying causes of Porphyria. Our database lists the following as having Porphyria as a symptom of that condition:

What causes Porphyria?

Causes: Porphyria: Excess production of heme and porphyrins
Heme is composed of porphyrin, a large circular molecule made from four rings linked together with an iron atom at its center. Heme is the oxygen-binding part of hemoglobin, giving red blood cells their color. It is also a component of several vital enzymes in the liver including the group known as cytochrome P450. This enzyme family is important in converting potentially harmful substances such as drugs to inactive products destined for excretion. (Source: Genes and Disease by the National Center for Biotechnology)

What triggers Porphyria?

The following conditions are listed as possible triggers for Porphyria:

Related information on causes of Porphyria:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Porphyria may be found in:

 

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