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Glossary for Primary biliary cirrhosis

  • Abdominal conditions: Medical conditions affecting the abdominal region.
  • Arthritis: General name for any type of joint inflammation, but often means age-related osteoarthritis.
  • Autoimmune diseases: A group of disorders in which the primary cause is the an inflammatory reaction caused by the body's own immune system attacking tissues
  • Biliary conditions: Medical conditions affecting the biliary system (liver, bile ducts, gallbladder, etc.) in digestion.
  • CREST syndrome: Group of symptoms usually related to systemic sclerosis
  • Cholangitis: bile duct inflammation (cholangitis)
  • Cholestyramine -- Teratogenic Agent: There is evidence to indicate that exposure to Cholestyramine (cholesterol-lowering drug) during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Chronic Hepatitis: Chronic hepatitis is defined as inflammatory disease of the liver lasting for more than six months.
  • Chronic liver disease: Any form of chronic liver disease
  • Cirrhosis of liver: Chronic liver disease wherein normal liver parenchyma is replaced by fibrous tissue.
  • Cirrhosis of the liver: Scarring of the liver from alcohol or other causes.
  • Digestive Diseases: Diseases that affect the digestive system
  • Dry eyes: Autoimmune disease damaging the eye tear ducts and other glands.
  • Fatigue: Excessive tiredness or weakness.
  • Fluid retention: Fluid retention in tissues
  • Hepatocellular jaundice: A condition which is characterized by jaundice due to injury or damage to the hepatocellular cells of the liver
  • Hyperpigmentation: Excess skin pigment or coloration
  • Inflammatory bowel disease: Inflammatory bowel disease refers to digestive symptoms resulting from chronic bowel inflammation. Crohn's disease and ulcerative colitis are two of the main subtypes of the disease. Scientists have discovered an array of genetic mutations which can result in an increased susceptibility to inflammatory bowel disease. Not all people with the genetic anomaly will develop the condition but it can increase the risk especially if other environmental factors are also present. The severity of the disease that develops is variable.
  • Itching skin: Itching feeling of the skin.
  • Jaundice: Bile or liver problem causing yellowness.
  • Liver conditions: Any condition that affects the liver
  • Liver failure: Acute liver failure (ALF) is an uncommon condition in which the rapid deterioration of liver function results in coagulopathy and alteration in the mental status of a previously healthy individual.
  • Osteoporosis: Bone thinning and weakening from bone calcium depletion.
  • Pancreatic cancer: Pancreatic cancer is a malignant neoplasm of the pancreas
  • Polychondritis: A serious, progressive, episodic condition characterized by inflammation and degeneration of cartilage in the body. The duration and severity of the episodes can vary.
  • Portal hypertension: Portal hypertension may be defined as a portal pressure gradient of 12 mm Hg or greater and is often associated with varices and ascites.
  • Primary sclerosing cholangitis: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown etiology that is recognized increasingly in children.
  • Sclerosing Cholangitis: Chronic hereditary disease causing inflammation and destruction of the bile ducts in and around the liver with subsequent blockage to bile flow
  • Secondary Biliary Cirrhosis: Secondary biliary cirrhosis is a condition where the bile ducts are unable to transport bile effectively due to a secondary cause which results in blockage, inflammation, scarring or some other damage to the bile ducts. The condition may result from such things as congenital defect of the bile ducts (e.g. biliary atresia), cystic fibrosis, gallstones or a variety of other secondary conditions.
  • Sjogren's Syndrome: Autoimmune disease damaging the eye tear ducts and other glands.
  • Skin bumps: Bumps or lumps on the skin.
  • Thyroid disorders: Any disorder of the thyroid gland.
  • Ursodeoxycholic Acid -- Teratogenic Agent: There is evidence to indicate that exposure to Ursodeoxycholic Acid during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Yellow eyes: Yellow color of the white of the eyes
  • Yellow skin: Yellow coloring affecting the skin

 

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