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Diseases » Pulmonary fibrosis » Glossary
 

Glossary for Pulmonary fibrosis

  • Aluminium lung: A respiratory condition caused by breathing in aluminium containing substances such as aluminium ore or a grain preservative called aluminium phosphide.
  • Amiodarone -- Teratogenic Agent: There is strong evidence to indicate that exposure to Amiodarone during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Amyloidosis: A rare group of metabolic disorders where a protein called amyloid accumulates in body organs and tissues where it can cause damage and is potentially fatal. Symptoms depend on the organs involved. There are numerous forms of the condition: primary amyloidosis, secondary amyloidosis, hemodialysis-associated amyloidosis and familial amyloidosis.
  • Breathing difficulties: Various types of breathing difficulty (dyspnea).
  • Bronchopulmonary dysplasia: A rare form of infant lung disease that usually occurs as a complication of ventilator use in premature babies.
  • Busulfan toxicity syndrome: Symptoms caused by the use of a chemotherapy drug called Busulfan.
  • Caplan's syndrome: Scarring and inflammation of lungs in people with rheumatoid arthritis who have also had exposure to coal dust. Also called rheumatoid pneumoconiosis.
  • Chemical poisoning -- Aluminum: Aluminum is a chemical used mainly for metallurgical purposes and can be found in packaging, electrical parts, vehicles, cooking utensils, construction materials and building components. The type and severity of symptoms varies depending on the amount of chemical involved and the nature of the exposure.
  • Chemical poisoning -- Tungsten: Tungsten is an element used mainly in light bulb filaments, X-ray tubes, electrodes, superalloys, heating elements and various other high temperature uses. Ingestion and other exposures to the chemical can cause various symptoms. The type and severity of symptoms varies depending on the amount of chemical involved and the nature of the exposure.
  • Chest conditions: Any condition affecting the chest
  • Chest discomfort: The sensation of discomfort that is located in the chest
  • Cough: The noise produced from the sudden expulsion of air from the lungs
  • Cystic Fibrosis: Cystic fibrosis is a hereditary disease affecting the exocrine (mucus) glands of the lungs, liver, pancreas, and intestines, causing progressive disability due to multisystem failure.
  • Dermatomyositis: A muscle disease characterized by chronic muscle inflammation resulting in progressive muscle weakness and a characteristic rash.
  • Dressler syndrome: A group of symptoms that can occur days, weeks or months after a heart attack or heart surgery. The symptoms may be due to such things as autoimmune processes, virus or bleeding around the heart which can result in inflammation of the membrane surrounding the heart.
  • Farmer's lung: A condition that affects farmers who are exposed to mouldy hay or crops. The lungs become inflamed due to a hypersensitivity reaction to the exposure.
  • Fibrosis: The formation of fibrous tissue
  • Graft-versus-host disease: A disease characterised by an immune response as a result of a transplantation or transfusion resulting in a widespread systemic inflammatory response
  • Graphite Pneumoconiosis: Lung damage caused by excessive inhalation of graphite. Cases are rare and severity can vary depending on the level of exposure.
  • Hand-Schuller-Christian Syndrome: A group of blood disorder involving excess production of histiocytes (type of immune cell) throughout the body. Accumulation of histiocytes results in non-cancerous growths which can damage organs and other body tissues such as bones. Symptom vary hugely and depend on location and size of tumor growths.
  • Hermansky-Pudlak Syndrome: A rare disorder characterized by various degrees of albinism, bleeding due to a platelet defect and accumulation of a waxy substance in cells (lysosomal ceroid storage).
  • Hermansky-Pudlak syndrome type 2: A rare disorder characterized by various degrees of albinism, bleeding due to a platelet defect, an accumulation of a waxy substance in cells (lysosomal ceroid storage) and immunodeficiency. HPS type 2 differs from type 1 in that it also involves immunodeficiency due to congenital neutropenia.
  • Hexamethonium -- Teratogenic Agent: There is evidence to indicate that exposure to Hexamethonium during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Human carcinogen -- Busulphan: Busulphan is deemed to be carcinogenic to humans. The carcinogenicity of the substance may be influenced by the duration and level of exposure.
  • Idiopathic Pulmonary Fibrosis: Lung fibrosis from unknown causes.
  • Interstitial lung disease: Any condition which affects the interstitium of the lungs
  • Labrador lung: A lung disease caused by breathing in dust containing silica and other inorganic compounds such as iron. The dusts deposit in the lungs where it can cause problems which may not become evident for many years. It is often seen in long-term miners.
  • Langerhans Cell Histiocytosis: A condition which is characterized by proliferation of Langerhans cells
  • Lung cancer: Lung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, which is the invasion of adjacent tissue and infiltration beyond the lungs. Most lung tumors are malignant.
  • Lung conditions: Various conditions affecting the lungs or related airways.
  • Lupus: Autoimmune disease with numerous effects on various organs and linings.
  • Lymphangioleiomyomatosis: A very rare progressive disease where an unusual type of muscle cell (smooth muscle) infiltrates the lungs which eventually obstructs the flow of air through the lungs. The cause is unknown and generally occurs in women of child bearing age.
  • Methotrexate -- Teratogenic Agent: There is evidence to indicate that exposure to Methotrexate during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Mitral stenosis: Narrowing of the mitral heart valve
  • Nitrofurantoin -- Teratogenic Agent: There is evidence to indicate that exposure to Nitrofurantoin during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Paracoccidioidomycosis: Infection by the fungus Paracoccidiodes brasiliensis which usually affects the lungs but can also involve the skin, mucous membranes, lymphatic system and other parts of the body.
  • Penicillamine -- Teratogenic Agent: There is evidence to indicate that exposure to Penicillamine during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Pneumoconiosis: A lung disease caused by breathing in air contaminated with particles of dust such as coal, kaolin, asbestos and talc. It is generally an occupation disease where people are exposed to the contaminated air for prolonged periods of time. Generally symptoms stop once the exposure ceases.
  • Pneumonia: Infection of the lung by bacteria, viruses or fungus.
  • Poor appetite: Loss or reduction in appetite for food
  • Possible human carcinogenic exposure -- Bleomycin: Some evidence indicates that exposure to Bleomycin has a possible link to an increased risk of developing cancer in humans. The carcinogenicity of the substance may be influenced by the duration and level of exposure. Bleomycin is used primarily as a chemotherapy drug.
  • Possible human carcinogenic exposure -- Mitomycin C: Some evidence indicates that exposure to Mitomycin C (a chemotherapy drug) has a possible link to an increased risk of developing cancer in humans. The carcinogenicity of the substance may be influenced by the duration and level of exposure.
  • Probable human carcinogen -- Chloramphenicol: Chloramphenicol (an antibiotic) is deemed to be a probable carcinogen to humans. The carcinogenicity of the substance may be influenced by the duration and level of exposure.
  • Pulmonary edema: Severe condition of excess fluid in the lungs.
  • Pulmonary hypertension: Pulmonary hypertension refers to high blood pressure in the blood vessels that carry blood to the lungs. Blood pressure in other parts of the body is normal or sometimes even low. The condition may be caused by such things as lung conditions (e.g. emphysema, chronic bronchitis), heart conditions (e.g. congestive heart failure, birth defects involving heart), AIDS or medications such as fenfluramine (a diet drug). Sometimes it occurs for no apparent reason and is called primary pulmonary hypertension.
  • Respiratory conditions: Any condition that affects the respiratory system
  • Rheumatoid arthritis: Autoimmune form of arthritis usually in teens or young adults.
  • Sarcoidosis: Rare autoimmune disease usually affecting the lungs.
  • Scleroderma: A rare, progressive connective tissue disorder involving thickening and hardening of the skin and connective tissue. There are a number of forms of scleroderma with some forms being systemic (involving internal organs).
  • Scleroderma, systemic: A rare autoimmune connective tissue disease where the body attacks parts of the body and causes scarring and thickness of the tissue. In the systemic form, the skin and organs are involved.
  • Shaver's disease: A progressive lung disorder caused by exposure to aluminium oxide which is present in bauxite fumes. The condition involves inflammation and damage to the air sacs in the lungs.
  • Shortness of breath: The feeling of being short of breath
  • Silicosis: An occupation lung disease caused by breathing in silica dust.
  • Sporotrichosis -- pulmonary: A fungal infection caused by the fungus Sporothrix schenckii. Usually only the skin is infected but bones, lungs and central nervous system can rarely be affected also. Transmission usually occurs through inhalation of the fungus.
  • Tuberous sclerosis: A rare genetic disorder characterized by harmartomatous skin nodules, seizures, phakomata and bone lesions.
  • Weakness: Symptoms causing weakness of the body
  • Weber-Christian disease: A rare skin disorder characterized by recurring inflammation of the fatty layer of the skin and the development of nodules.
  • Wegener's granulomatosis: A rare disease involving blood vessel inflammation which can affect the blood flow to various tissues and organs and hence cause damage. The respiratory system and the kidneys are the main systems affected.
  • Weight loss: Loss of body weight.
  • Whipple's Disease: Rare malabsorption disease from bacterial digestive infection

 

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