Clinical Trials for Pulmonary fibrosis
Clinical trials are research studies conducted in an effort to improve overall patient health and care.
Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition.
Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks.
A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.
A brief description of each phase:
- Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
- Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
- Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
- Phase IV: These studies monitor long-term side effects after the treatment has been marketed.
Clinical Trials data for Pulmonary fibrosis is grouped into the following categories:-
The format for each of the following is:
- The name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
- followed by a list of drug/s, if any, used in the trial
ClinicalTrials.gov has listed the following trials for Pulmonary fibrosis:
- Pirfenidone for the Treatment of Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis (PF/IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Pirfenidone
- Gleevec Idiopathic Pulmonary Fibrosis (IPF) Study - This study has been completed (Current: 23 Nov 2006) - Imatinib Mesylate (Gleevec)
- The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006) - Interferon gamma-1b ("Actimmune")
- An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF - This study is no longer recruiting patients (Current: 23 Nov 2006) - Interferon gamma-1b
- Lung Disease Associated With Rheumatoid Arthritis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Specimen Collection for Individuals With Lung Disease Associated With Rheumatoid Arthritis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Specimen Procurement From People With Hereditary Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Study Evaluating the Safety and Efficacy of Etanercept in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Etanercept
- Safety and Tolerability Study of FG-3019 in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006) - FG-3019
- Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone (Deskar),Pirfenidone
- Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Role of Helicobacter Pylori and Its Toxins in Lung and Digestive System Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
- A Randomized, Double-Blind, Three-Arm, Phase 3b Study Comparing the Safety and Efficacy of Interferon Gamma-1b With Azathioprine, and Azathioprine Alone in Patients With IPF Receiving Prednisone - This study has been terminated (Current: 23 Nov 2006) - interferon-gamma 1b,azathioprine
- An Open-Label Study of the Safety and Efficacy of Subcutaneous Recombinant Interferon-Gamma 1b (IFN-Gamma 1b) in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006) - interferon-gamma 1b
- Inhaled Iloprost in Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Iloprost Inhalation Solution (Ventavis)
- Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study is currently recruiting patients (Current: 23 Nov 2006) - GC1008, Human Anti-Transforming Growth Factor-b 1, 2, 3 mAb
- Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension - This study is currently recruiting patients (Current: 23 Nov 2006) - Sildenafil (50 mg)
- Efficacy and Safety of Oral Bosentan in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006) - bosentan
- Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study - This study is currently recruiting patients (Current: 23 Nov 2006) - minocycline
- BUILD 3: Bosentan Use in Interstitial Lung Disease - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - bosentan
- Diffuse Fibrotic Lung Disease - This study has been completed (Current: 23 Nov 2006) - prednisone,cyclophosphamide,dapsone
- Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
- Segmental Bronchoalveolar Lavage - This study is currently recruiting patients (Current: 23 Nov 2006)
- Scleroderma Lung Study - This study has been completed (Current: 23 Nov 2006) - cyclophosphamide,azathioprine
- Idiopathic Pulmonary Fibrosis: a Case-Control Study - This study has been completed (Current: 23 Nov 2006)
- Idiopathic Pulmonary Fibrosis--Pathogenesis and Staging - SCOR in Occupational and Immunological Lung Diseases - This study has been completed (Current: 23 Nov 2006)
- Linkage Study in Familial Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006)
- Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma - This study is no longer recruiting patients (Current: 23 Nov 2006) - Bosentan
- Microarray Analysis of Gene Expression in IPF - This study is currently recruiting patients (Current: 23 Nov 2006)
- Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF) - This study is currently recruiting patients (Current: 23 Nov 2006)
- Genomic and Proteomic Analysis of Disease Progression in IPF - This study is currently recruiting patients (Current: 23 Nov 2006)
- A Study of the Safety and Efficacy Interferon-Gamma 1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006) - Interferon-gamma 1b
- A Study of the Safety and Clinical Effects of Interferon Gamma-1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006) - Interferon-gamma 1b
- Safety Study of Tetrathiomolybdate in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006) - Tetrathiomolybdate
- Evaluation of Patients With Idiopathic Pulmonary Fibrosis (IPF) Through an IPF Registry - This study is currently recruiting patients (Current: 23 Nov 2006)
- A Pilot Study of Aerosol Interferon-Gamma Treatment in Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006) - Aerosol Interferon-gamma treatment
- Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - zileuton,azathioprine/prednisone
- Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
- Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
- Treatment of Idiopathic Pulmonary Fibrosis With Thalidomide - This study is currently recruiting patients (Current: 23 Nov 2006) - Thalidomide
- Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation - This study is currently recruiting patients (Current: 23 Nov 2006)
- Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006) - sildenafil
- The Safety and Effectiveness of Zidovudine in the Treatment of HIV-Infected Children With Mild to Moderate Symptoms - This study has been completed (Current: 23 Nov 2006) - Zidovudine
- Database of Interstitial Lung Diseases - This study is currently recruiting patients (Current: 23 Nov 2006)
- Pulmonary Rehabilitation in Interstitial Lung Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
- Herpesvirus in Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
The format for each of the following is:
- The drug,
- followed by the name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
ClinicalTrials.gov has listed the following drugs in trials for Pulmonary fibrosis:
- Aerosol Interferon-gamma treatment - A Pilot Study of Aerosol Interferon-Gamma Treatment in Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006)
- Azathioprine/Prednisone - Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Azathioprine - A Randomized, Double-Blind, Three-Arm, Phase 3b Study Comparing the Safety and Efficacy of Interferon Gamma-1b With Azathioprine, and Azathioprine Alone in Patients With IPF Receiving Prednisone - This study has been terminated (Current: 23 Nov 2006)
- Azathioprine - Scleroderma Lung Study - This study has been completed (Current: 23 Nov 2006)
- Bosentan - BUILD 3: Bosentan Use in Interstitial Lung Disease - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
- Bosentan - Efficacy and Safety of Oral Bosentan in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Bosentan - Efficacy and Safety of Oral Bosentan in Pulmonary Fibrosis Associated With Scleroderma - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Cyclophosphamide - Diffuse Fibrotic Lung Disease - This study has been completed (Current: 23 Nov 2006)
- Cyclophosphamide - Scleroderma Lung Study - This study has been completed (Current: 23 Nov 2006)
- Dapsone - Diffuse Fibrotic Lung Disease - This study has been completed (Current: 23 Nov 2006)
- Etanercept - Study Evaluating the Safety and Efficacy of Etanercept in Patients With Idiopathic Pulmonary Fibrosis - This study is no longer recruiting patients (Current: 23 Nov 2006)
- FG-3019 - Safety and Tolerability Study of FG-3019 in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006)
- GC1008, Human Anti-Transforming Growth Factor-b 1, 2, 3 mAb - Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study is currently recruiting patients (Current: 23 Nov 2006)
- Iloprost Inhalation Solution (Ventavis) - Inhaled Iloprost in Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Imatinib Mesylate (Gleevec) - Gleevec Idiopathic Pulmonary Fibrosis (IPF) Study - This study has been completed (Current: 23 Nov 2006)
- Interferon gamma-1b ("Actimmune") - The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Interferon gamma-1b - An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Interferon-Gamma 1B - A Randomized, Double-Blind, Three-Arm, Phase 3b Study Comparing the Safety and Efficacy of Interferon Gamma-1b With Azathioprine, and Azathioprine Alone in Patients With IPF Receiving Prednisone - This study has been terminated (Current: 23 Nov 2006)
- Interferon-Gamma 1B - An Open-Label Study of the Safety and Efficacy of Subcutaneous Recombinant Interferon-Gamma 1b (IFN-Gamma 1b) in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006)
- Interferon-gamma 1b - A Study of the Safety and Clinical Effects of Interferon Gamma-1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006)
- Interferon-gamma 1b - A Study of the Safety and Efficacy Interferon-Gamma 1b in Patients With Idiopathic Pulmonary Fibrosis (IPF) - This study has been completed (Current: 23 Nov 2006)
- Minocycline - Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study - This study is currently recruiting patients (Current: 23 Nov 2006)
- Pirfenidone (Deskar) - Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
- Pirfenidone - Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
- Pirfenidone - Pirfenidone for the Treatment of Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis (PF/IPF) - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Pirfenidone - Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Pirfenidone - Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Prednisone - Diffuse Fibrotic Lung Disease - This study has been completed (Current: 23 Nov 2006)
- Sildenafil (50 mg) - Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension - This study is currently recruiting patients (Current: 23 Nov 2006)
- Sildenafil - Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Tetrathiomolybdate - Safety Study of Tetrathiomolybdate in Patients With Idiopathic Pulmonary Fibrosis - This study has been completed (Current: 23 Nov 2006)
- Thalidomide - Treatment of Idiopathic Pulmonary Fibrosis With Thalidomide - This study is currently recruiting patients (Current: 23 Nov 2006)
- Zidovudine - The Safety and Effectiveness of Zidovudine in the Treatment of HIV-Infected Children With Mild to Moderate Symptoms - This study has been completed (Current: 23 Nov 2006)
- Zileuton - Zileuton for the Treatment of Idiopathic Pulmonary Fibrosis - This study is currently recruiting patients (Current: 23 Nov 2006)
The trial data on this page has been sourced from
