Glossary for Purpura

• ATRUS syndrome: A rare syndrome characterized by fusion of the forearm bones near the elbow and a blood disorder.
• Adrenal hemorrhage, neonatal: Hemorrhage of the adrenal gland after birth. The severity of the disorder is varies from a small hemorrhage to damage to the whole adrenal gland. Sometimes the condition is discovered incidentally during ultrasounds for other reasons. The hemorrhage may occur as the result of a variety of causes including adrenal tumor, neonatal stress, and blood coagulation disorder or for no apparent reason.
• Amyloidosis: A rare group of metabolic disorders where a protein called amyloid accumulates in body organs and tissues where it can cause damage and is potentially fatal. Symptoms depend on the organs involved. There are numerous forms of the condition: primary amyloidosis, secondary amyloidosis, hemodialysis-associated amyloidosis and familial amyloidosis.
• Angioneurotic Edema: Recurring periods of noninflammatory swelling involving the skin, intestinal organs, brain and mucous membranes. In severe cases, respiratory swelling can result in compromised breathing.
• Anorexia Nervosa: A disorder where a distorted sense of body image leads to self-starvation to the point of death in some cases.
• Antisynthetase syndrome: A rare autoimmune disease that affects the muscles. It involves the development of antibodies to an enzyme (aminoacyl-tRNA synthetase) which is involved in making proteins.
• Asphyxiation: A condition which is characterized by the inability to respire
• Autoimmune Thrombocytopenia: Autoimmune disorder causing a lack of blood platelets.
• Autoimmune Vasculitis: A inflammation of the blood vessels caused by an autoimmune reaction
• Autoimmune diseases: A group of disorders in which the primary cause is the an inflammatory reaction caused by the body's own immune system attacking tissues
• Bleeding and coagulation conditions:
• Bleeding under the skin: A condition which is characterized by the loss of blood from blood vessels under ones skin
• Blood conditions: Conditions that affect the blood
• Blood vessel conditions: Conditions that affect the blood vessels
• Bruising: Bleeding under skin leading to discoloration.
• Chemical poisoning -- Para-Dichlorobenzene: Para-Dichlorobenzene is a chemical used mainly as a pesticide, mold and mildew preventer, moth repellent and toilet deodorant. Ingestion and other exposures to the chemical can cause various symptoms. The type and severity of symptoms varies depending on the amount of chemical involved and the nature of the exposure.
• Child abuse: Physical, sexual, emotional abuse or neglect of child.
• Ecchymosis: A small haemorrhagic spot in the skin or mucous membrane.
• Ehlers-Danlos syndrome, classic type: A rare genetic connective tissue disorder characterized by hypermobile joints, joint dislocations and skin hyperextensibility and fragility - a combination of ED types I and II.
• Endocarditis: Inflammation of the inner lining of the heart
• Familial myelofibrosis: A rare condition where progressive scarring or fibrosis of the bone marrow impairs it's ability to make blood cells causing symptoms such as anemia and liver and spleen enlargement.
• Gardner-Diamond syndrome: A rare inherited disorder characterized by bruises which form readily, tend to spread and are painful. Some cases are believed to have a psychological basis.
• Gaucher disease -- perinatal lethal form: A rare syndrome characterized by the association of abnormally tight skin and Gaucher disease which is a lipid storage disease. This is the most severe form of Gaucher disease.
• Heatstroke: Heat exhaustion and collapse from heat exposure
• Hemangioma thrombocytopenia syndrome: A rare condition characterized by a spreading congenital hemangioma (collection of abnormal blood vessels) usually on the skin as well as blood clotting problems.
• Hemolytic uremic syndrome: A rare condition characterized by acute kidney failure, hemolytic anemia and thrombocytopenia (reduced blood platelet count). The condition is often caused by upper respiratory infections or infectious diarrhea.
• Hemorrhagic fever: A group of diseases caused by viruses which cause damage to blood vessels and result in hemorrhages and fever. The hemorrhaging does not always cause serious bleeding. The specific symptoms may vary depending on which particular virus is involved.
• Hemorrhagic rash: Skin rash caused by bleeding under the skin
• Hoyeraal-Hreidarsson syndrome: A very rare syndrome characterized mainly by retarded growth, a small head, anemia, immunodeficiency and an underdeveloped brain (cerebellum).
• Immune Thrombocytopenic Purpura: Reduced blood platelets causing visible skin blemishes from bleeding or bruising.
• Immune thrombocytopenia: A rare disorder where the body's immune system attacks blood platelets which affect the blood's ability to clot.
• Immunoglobulinic amyloidosis: A disease characterized by the abnormal deposit of amyloid in various parts of the body, especially organs such as the kidneys, heart, liver, gastrointestinal tract and peripheral nerves. It occurs when plasma cells in the bone marrow produce too much of a protein portion of an antibody called the light chain. The exact symptoms are determined by the extent of the organ involvement.
• Leptospirosis: Bacterial infection usually caught from animal urine.
• Leukocytoclastic angiitis -- cutaneous: Inflammation of small blood vessels in the skin. It may occur for no obvious reason or may be associated with conditions such as collagen vascular disorders, certain infections and certain drugs or foods.
• Leukocytoclastic angiitis -- systemic: Inflammation of small blood vessels. Usually the small blood vessels in the skin are involved but sometimes small blood vessels in other organs such as joints, kidneys, and gastrointestinal tract may be involved. Symptoms become more serious once there is systemic (organ) involvement and death may result in some severe cases.
• Lymphocytic vasculitis: Blood vessel inflammation due to infiltration of blood vessel walls with lymphocytes which can causes raised skin welts which can be tender and painful. The skin often remains darkened after the lesions are resolved.
• Onychotrichodysplasia and neutropenia: A very rare syndrome characterized mainly by nail, hair and blood abnormalities.
• Perinatal-lethal Gaucher disease: A disorder caused by a deficiency of an enzyme called glucocerebrosidase. The foetal form is one of several forms of Gaucher disease and is the rarest. The fetal form causes death before birth or soon after.
• Petechiae: A red spot due to the escape of a small amount of blood.
• Purpura simplex: Bruising condition mostly in women
• Relapsing fever: Tick-borne disease with symptoms that resolve and then relapse
• Scurvy: Severe disease from vitamin C deficiency
• Senile purpura: Bruising condition mostly in the elderly
• Skin conditions: Any condition that affects the skin
• Thrombocytopenia: Decreased platelets in the blood
• Vasculitis: Inflammation of a blood or lymph vessel
• Vasculitis hypersensitivity: A condition which is characterised by a reaction that results in the inflammation of the blood vessels
• Vibrio vulnificus: Bacteria commonly infecting oysters and seafood.
• Weil's syndrome: Severe form of Leptospirosis

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