What is SAPHO syndrome?

What is SAPHO syndrome?

• SAPHO syndrome: A rare disorder involving skin (acne, pustulosis), bone (hyperostosis, osteitis) and joint problems.
• SAPHO syndrome: Syndrome consisting of synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis (SAPHO). The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome.
  Source - Diseases Database

SAPHO syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that SAPHO syndrome, or a subtype of SAPHO syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list SAPHO syndrome as a "rare disease".
Source - Orphanet

SAPHO syndrome: Introduction

Types of SAPHO syndrome:

Broader types of SAPHO syndrome:

• Acne-like conditions
• Skin conditions
• Joint conditions
• Bone or skeletal conditions
• Musculoskeletal conditions
• Limb conditions
• more types...»

How serious is SAPHO syndrome?

Prognosis of SAPHO syndrome: prolonged unpredictable course
Complications of SAPHO syndrome: see complications of SAPHO syndrome

What causes SAPHO syndrome?

Causes of SAPHO syndrome: see causes of SAPHO syndrome

What are the symptoms of SAPHO syndrome?

Symptoms of SAPHO syndrome: see symptoms of SAPHO syndrome

Complications of SAPHO syndrome: see complications of SAPHO syndrome

SAPHO syndrome: Testing

Misdiagnosis: see misdiagnosis and SAPHO syndrome.

How is it treated?

Doctors and Medical Specialists for SAPHO syndrome: Orthopedic surgeon ; see also doctors and medical specialists for SAPHO syndrome.
Treatments for SAPHO syndrome: see treatments for SAPHO syndrome
Research for SAPHO syndrome: see research for SAPHO syndrome

Name and Aliases of SAPHO syndrome

Main name of condition: SAPHO syndrome

Synovitis - acne - pustulosis - hyperostosis - osteitis, Synovitis acne pustulosis hyperostosis osteitis, synovitis, acne, pustulosis, hyperostosis, osteomyelitis, Acquired hyperostosis syndrome, Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis

Acquired hyperostosis syndrome Source - Diseases Database

Acquired hyperostosis syndrome, Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)

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