SAPHO syndrome: A rare disorder involving skin (acne, pustulosis), bone (hyperostosis, osteitis) and joint problems. More detailed information about the symptoms, causes, and treatments of SAPHO syndrome is available below.
See full list of 20 symptoms of SAPHO syndrome
Read more about complications of SAPHO syndrome.
Read more about causes of SAPHO syndrome.
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Read more about Misdiagnosis and SAPHO syndrome
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Prognosis for SAPHO syndrome: prolonged unpredictable course
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Types of SAPHO syndrome
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Syndrome consisting of synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis (SAPHO). The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome. - (Source - Diseases Database)
SAPHO syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that SAPHO syndrome, or a subtype of SAPHO syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list SAPHO syndrome as a "rare disease".
Source - Orphanet
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