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Diseases » SCID » Glossary

Glossary for SCID

  • ADA Deficiency: Adenosine deaminase deficiency is a condition which is inherited that results severe combined immunodeficiency disease.
  • AIDS: A term given to HIV patients who have a low CD4 count (below 200) which means that they have low levels of a type of immune cell called T-cells. AIDS patients tend to develop opportunistic infections and cancers. Opportunistic infections are infections that would not normally affect a person with a healthy immune system. The HIV virus is a virus that attacks the body's immune system.
  • Adenosine deaminase deficiency: A rare disorder where a deficiency in the activity of adenosine deaminase causes severe immunodeficiency which in turn results in frequent severe bacterial, viral and fungal infections.
  • Chickenpox: Common viral infection.
  • Chronic Granulomatous Disease: A very rare inherited blood disorder where certain cells involved with immunity (phagocytes) are unable to destroy bacteria and hence the patient suffers repeated bacterial infections.
  • Common Variable Immunodeficiency: An immunodeficiency disorder involving low blood gamma globulin levels which results in an increased susceptibility to infections. The condition may be inherited or can be caused by certain drugs (levamisole, hydantoin and carbamazepine).
  • DiGeorge syndrome: 22q11.2 deletion syndrome is a genetic disorder which can result in a vast array of symptoms. Various names have been used to describe different manifestations of the syndrome. Di George Syndrome primarily involves an underdeveloped thymus and parathyroid glands which results in lowered immunity low blood calcium levels respectively. Another primary feature is heart defects. Various other variable features are also present. It is not uncommon for patients to have more than one of the 22q11.2 deletion syndrome subtypes which can make diagnosis confusing - other subtypes include Sphrintzen syndrome, Caylor cardiofacial syndrome and CATCH 22.
  • Genetic Disease: Any disease that is handed down to oneself through the chromosomes of ones parents
  • Graft-versus-host disease: A disease characterised by an immune response as a result of a transplantation or transfusion resulting in a widespread systemic inflammatory response
  • HIV/AIDS: HIV is a sexually transmitted virus and AIDS is the progressive immune failure that HIV causes.
  • Hyper-IgM Syndrome: A rare inherited immunodeficiency disorder which causes frequent infections involving the ears, eyes, sinuses, lungs, skin, respiratory tract and other areas of the body.
  • Immune deficiency conditions: Any of various diseases that suppress the immune system.
  • Immune disorders: Disorders that affect the immune system
  • Measles: Once common viral infection now rare due to vaccination.
  • Meningitis: Dangerous infection of the membranes surrounding the brain.
  • Omenn syndrome: A rare inherited disorder of the immune system involving B and T lymphocytes and characterized by skin rash and frequent infections.
  • Pneumonia: Infection of the lung by bacteria, viruses or fungus.
  • Primary Immune Deficiency: Various types of immune deficiencies; usually genetic.
  • Recurrent infections: Recurrent infections that occur throughout the year.
  • SCID: Major failure of the immune system, usually genetic.
  • Selective IgA Deficiency: Immune deficiency from lacking immunoglobulin A (IgA) antibodies.
  • Sepsis: The presence of pathological micro-organisms in the blood
  • X-Linked Agammaglobulinemia: Immune deficiency from lack of antibodies.


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