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Causes of Selective IgA Deficiency

Causes of Selective IgA Deficiency

Most cases of selective IgA deficiency are caused by inherited or sporadic mutations in specific genes. However, selective IgA deficiency can also be due to certain drugs.

Race Patterns for Selective IgA Deficiency Causes:

Racial Details for Selective IgA Deficiency: Among those with this disease, people of European ancestry greatly outnumber those of other ethnic... (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID) ...more »

Selective IgA Deficiency: Related Medical Conditions

To research the causes of Selective IgA Deficiency, consider researching the causes of these these diseases that may be similar, or associated with Selective IgA Deficiency:

Selective IgA Deficiency: Causes and Types

Causes of Broader Categories of Selective IgA Deficiency: Review the causal information about the various more general categories of medical conditions:

Selective IgA Deficiency as a symptom:

Conditions listing Selective IgA Deficiency as a symptom may also be potential underlying causes of Selective IgA Deficiency. Our database lists the following as having Selective IgA Deficiency as a symptom of that condition:

What causes Selective IgA Deficiency?

Article excerpts about the causes of Selective IgA Deficiency:
IgA deficiency is caused by faulty white blood cells called B cells or B lymphocytes. While patients have normal numbers of B cells, these cells do not mature into normal IgA-producing cells. Scientists do not yet know the exact cause or causes for these immature B cells. Sometimes clusters of cases occur in families, and IgA-deficient patients are more likely than the general population to be related to someone with combined variable immunodeficiency, another form of immunodeficiency discussed below. Research is underway to determine the location of the suspected genes on the involved chromosomes.

How is IgA deficiency treated?

There is no specific treatment for selective IgA deficiency. Doctors treat bacterial infections with antibiotics, and patients with giardiasis (an infection caused by a common intestinal parasite receive metronidazole or quinacrine hydrochloride. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)

Related information on causes of Selective IgA Deficiency:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Selective IgA Deficiency may be found in:

 

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