Symptoms of Selective IgA Deficiency
Symptoms of Selective IgA Deficiency
The list of signs and symptoms mentioned in various sources
for Selective IgA Deficiency includes the 12
symptoms listed below:
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Selective IgA Deficiency: Complications
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Diagnostic Testing
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Do I have Selective IgA Deficiency?
Wrongly Diagnosed with Selective IgA Deficiency?
The list of other diseases or medical conditions
that may be on the differential diagnosis list of alternative diagnoses
for Selective IgA Deficiency includes:
See the full list of 18
More about symptoms of Selective IgA Deficiency:
More information about symptoms of Selective IgA Deficiency and related conditions:
Other Possible Causes of these Symptoms
Click on any of the symptoms below to see a full list
of other causes including diseases, medical conditions, toxins, drug interactions,
or drug side effect causes of that symptom.
Article Excerpts About Symptoms of Selective IgA Deficiency:
Many IgA-deficient patients are
healthy, with no more than the usual number of infections. Those
patients who do have symptoms typically have recurring ear, sinus,
or lung infections that may not respond to standard courses of
antibiotics. People with IgA-deficiency are likely to have other
problems, including allergies, asthma, chronic diarrhea, and
autoimmune diseases.
How is IgA deficiency
diagnosed?
People with IgA deficiency have low
levels of IgA antibodies in their blood. In contrast, their levels
of IgM and IgG immunoglobulins usually are normal. IgA-deficient
people also have normal levels of other immune system cells,
including T cells, phagocytes, and complement proteins.
Doctors diagnose IgA deficiency by doing tests to measure
the amount of total immunoglobulin in the blood as well as the type
of immunoglobulin known as IgG2. Other tests determine how well a
person is producing antibodies against specific germs following
immunization with a common vaccine, such as a tetanus
shot.
What causes IgA
deficiency?
IgA deficiency is caused by faulty
white blood cells called B cells or B lymphocytes. While patients
have normal numbers of B cells, these cells do not mature into
normal IgA-producing cells. Scientists do not yet know the exact
cause or causes for these immature B cells. Sometimes clusters of
cases occur in families, and IgA-deficient patients are more likely
than the general population to be related to someone with combined
variable immunodeficiency, another form of immunodeficiency
discussed below. Research is underway to determine the location of
the suspected genes on the involved chromosomes.
How is IgA deficiency
treated?
There is no specific treatment for
selective IgA deficiency. Doctors treat bacterial infections with
antibiotics, and patients with giardiasis (an infection caused by a
common intestinal parasite receive metronidazole or quinacrine
hydrochloride.
(Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)
Medical articles and books on symptoms:
These general reference articles may be of interest
in relation to medical signs and symptoms of disease in general:
Full list of premium articles on symptoms and diagnosis
About signs and symptoms of Selective IgA Deficiency:
The symptom information on this page
attempts to provide a list of some possible signs and symptoms of Selective IgA Deficiency.
This signs and symptoms information for Selective IgA Deficiency has been gathered from various sources,
may not be fully accurate,
and may not be the full list of Selective IgA Deficiency signs or Selective IgA Deficiency symptoms.
Furthermore, signs and symptoms of Selective IgA Deficiency may vary on an individual basis for each patient.
Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they
are indeed Selective IgA Deficiency symptoms.