What is Soto's Syndrome?

What is Soto's Syndrome?

• Soto's Syndrome: A rare hereditary disorder characterized by excessive growth during the first few years of life as well as various other mental and physical anomalies.
• Soto's Syndrome: Increased birth weight with excessive growth during the first four years of life, macrocephaly, characteristic facial features, nonprogressive cerebral disorder and mental retardation.
  Source - Diseases Database

Soto's Syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Soto's Syndrome, or a subtype of Soto's Syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Soto's Syndrome as a "rare disease".
Source - Orphanet

Soto's Syndrome: Introduction

Types of Soto's Syndrome:

Broader types of Soto's Syndrome:

• Brain conditions
• Genetic Disease
• Genetic conditions
• Growth conditions
• Mental retardation conditions
• Intellectual or developmental disabilities
• Head conditions
• Muscle conditions
• Speech and communication conditions
• Ear and hearing conditions
• more types...»

How many people get Soto's Syndrome?

Prevalance of Soto's Syndrome: rare
Incidence (annual) of Soto's Syndrome: estimated 1 per 5,000 newborns have Sotos syndrome which includes reported cases and undiagnosed cases, Genetics Home Reference website
Incidence Rate of Soto's Syndrome: approx 1 in 5,000 or 0.02% or 54,400 people in USA [about data]

Who gets Soto's Syndrome?

Patient Profile for Soto's Syndrome: Children.

How serious is Soto's Syndrome?

Prognosis of Soto's Syndrome: Moderate. Normal life expectancy with some possible mental deficits.
Complications of Soto's Syndrome: see complications of Soto's Syndrome
Prognosis of Soto's Syndrome: Soto's syndrome is not a life-threatening disorder and patients may have a normal life expectancy. The initial abnormalities of Soto's syndrome usually resolve as the growth rate becomes normal after the first few years of life. Developmental delays may improve in the school-age years, however, coordination problems may persist into adulthood. (Source: excerpt from NINDS Soto's Syndrome Information Page: NINDS)

What causes Soto's Syndrome?

Causes of Soto's Syndrome: see causes of Soto's Syndrome

What are the symptoms of Soto's Syndrome?

Symptoms of Soto's Syndrome: see symptoms of Soto's Syndrome

Complications of Soto's Syndrome: see complications of Soto's Syndrome

Can anyone else get Soto's Syndrome?

Contagion of genetic conditions: generally not; see details in contagion of genetic diseases.
Inheritance: see inheritance of Soto's Syndrome

Inheritance of genetic conditions: see details in inheritance of genetic diseases.

Soto's Syndrome: Testing

Diagnostic testing: see tests for Soto's Syndrome.

Misdiagnosis: see misdiagnosis and Soto's Syndrome.

How is it treated?

Doctors and Medical Specialists for Soto's Syndrome: Neurologist ; see also doctors and medical specialists for Soto's Syndrome.
Treatments for Soto's Syndrome: see treatments for Soto's Syndrome
Research for Soto's Syndrome: see research for Soto's Syndrome

Organs Affected by Soto's Syndrome:

Organs and body systems related to Soto's Syndrome include:

• Brain

Name and Aliases of Soto's Syndrome

Main name of condition: Soto's Syndrome

Class of Condition for Soto's Syndrome: genetic

Cerebral Gigantism, Sotos sequence, Distinctive facial appearance, overgrowth in childhood, and learning disabilities or delayed development

Cerebral gigantism Source - Diseases Database

Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)

Soto's Syndrome: Related Conditions

Research the causes of these diseases that are similar to, or related to, Soto's Syndrome:

• Cerebral gigantism
• Mental retardation
• Hypotonia
• Macrocrania
• Developmental delay

Search Specialists by State and City